Giant hemangioma or metastatic disease of malignant gastrointestinal
tumor? Diagnoses through ‘new-line’ therapy
D Jost, C Stroszczynski, G Gaffke, P
Hohenberger,
and R Felix
Klinik und Poliklinik für Strahlenheilkunde,
Universitätsklinikum Charitie, Campus-Buch, Robert-Roessle-Klinik
im Helios Klinikum, Berlin, Germany
Klinik
für Chirurgie und Chirurgische Onkologie, Universitätsklinikum Charitie,
Campus-Buch, Robert-Roessle-Klinik im Helios Klinikum, Berlin, Germany
Corresponding address: Mr D Jost,
Klinik und Poliklinik für Strahlenheilkunde,
Universitätsklinikum Charitie, Campus-Buch, Robert-Roessle-Klinik
im Helios Klinikum, Linderberger Weg 80, 13125 Berlin, Germany
Email: jostdominik@gmx.de
Abstract
Centripetal enhancement of liver lesions on
MRI scanning is an almost specific finding in the diagnosis of
benign hemangiomata. The ability of MRI to produce higher temporal
resolution of dynamic measurements shows that malignant liver
lesions can also demonstrate centripetal enhancement. We report
here a case of a malignant gastrointestinal stromal tumor (GIST)
with a huge hepatic metastatic lesion of undetermined origin.
During therapy with Imatinib (Glivec® , Novartis, Basel, Switzerland), a highly selective tyrosine
kinase inhibitor, the lesion shrank markedly and exhibited changes
in contrast enhancement.
Key words
GIST, liver, metastatic disease, hemangioma
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