Thrombotic thrombocytopenic purpura (TTP) associated with interferon therapy of hepatitis C
Iryna S. Hepburn and Robert Schade
Corresponding address:
Robert Schade, MD, Department of Medicine, Medical College of Georgia,
1120 15th Street, BBR2540, Augusta, GA 30912, USA.
E-mail: rschade@mail.mcg.edu
Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome (TTP/HUS) is a rare but known complication of chronic viral hepatitis C (HCV). Even less frequently treatment of HCV with interferon-alpha (INFα) may become complicated with TTP/HUS, although only a few such reports have been published. We report a 43-year-old woman who developed TTP on two separate occasions soon after beginning treatment with IFN-alpha and ribavarin for HCV.
Keywords
Thrombotic thrombocytopenic purpura (TTP); hepatitis C; interferon.
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