Metastatic prostate cancer presenting with hoarseness
by Irina Rybalova, Claudia F. E. Kirsch, Jin K. Choe and Basil S. Kasimis
Metastatic involvement resulting in voice alteration may occur from vocal cord infiltration or recurrent laryngeal nerve involvement. We present a case of metastatic prostate adenocarcinoma to the left infrahyoid neck compressing the larynx resulting in hoarseness. A case report with one-year follow-up is presented. The patient is a 65-year-old male with hoarseness and a left infrahyoid prostate metastases measuring 8 by 10 cm, effacing the left pyrifom sinus and shifting the true and false vocal cords to the right of midline, with cord morphology and mobility maintained. Definitive radiation therapy reduced the infrahyoid metastases with resolution of hoarseness. Phonatory alteration from metastatic prostate carcinoma is rare. We present a case of hoarseness resulting from displacement of the larynx from infrahyoid metastases, which resolved after reduction in size of the metastases with radiation therapy.
(Oncology, Ear, nose and throat; May 2005) More...

Hypothyroidism presenting as recurrence of previously surgically decompressed carpal tunnel syndrome
by V. Reid, A. S. M. Jawad and J. D. Perry
We report the case history of a 45-year-old woman who presented with symptoms of bilateral carpal tunnel syndrome 8 years after a successful surgical decompression of both tunnels. (Endocrinology, General surgery; April 2005) More...

Renal colic: an unusual presentation of non-Hodgkin's lymphoma of the urinary bladder
Secondary involvement of the urinary bladder in non-Hodgkin's lymphoma is relatively common, but primary malignant lymphomas of this organ remain exceedingly rare. We report a case presenting atypically with renal colic and briefly review the relevant literature(May 2004)More...

Squamous cell carcinoma complicating chronic osteomyelitis
The internal fixation of fractures is associated with a risk of infection. Open fractures in particular are susceptible to such infection. Treatment is difficult and patients can develop a chronic osteomyelitis. We present the case of a patient who developed chronic osteomyelitis with a persistent discharging sinus following internal fixation of an open fracture of tibia. (March 2004) More...

Foster Kennedy syndrome secondary to oligodendroglioma
Foster Kennedy syndrome (FKS) is rare.It is characterised by the presence of ipsilateral optic atrophy,contralateral papilloedema and ipsilateral anosmia.Since its first description in 1911, it has never been reported in oligodendroglioma. (January 2004) More...

Giant hemangioma or metastatic disease of malignant gastrointestinal tumor? Diagnoses through ‘new-line’ therapy
In a case of a malignant gastrointestinal stromal tumor (GIST) with a huge hepatic metastatic lesion of undetermined origin, the lesion shrank markedly during therapy with a highly selective tyrosine kinase inhibitor. (June 2003) More...

Paraneoplastic Syndrome Presenting as Progressive Cognitive Decline
A number of paraneoplastic neurological syndromes have been described in association with small cell lung carcinoma and, less commonly, with other malignancies. We describe here the case of a 58-year-old woman with paraneoplastic limbic encephalitis (PLE) complicating squamous cell carcinoma of the lung. (August 2002) More...

Atypical Metastases From Squamous Cell Cancers
Relapse of squamous cell carcinomas usually occurs in a predictable pattern. We present two patients with rare metastases. The first developed peritoneal disease without evidence of intra-thoracic spread due to a laryngeal cancer. The second, a patient with a vulval squamous tumour, was presented with distant disease following foot pain. (July 2002) More...

An Unusual Primary Pulmonary Carcinoma
ACC is an unusual pulmonary neoplasm, accounting for 0.09%-0.2% of all lung cancers. It is a low-grade tumour with unusual histological features and rarely metastasises outside the lungs. We describe a case with bilateral renal metastases. (July 2002) More...