Diabetic ketoacidosis and prolonged hyperchloraemic acidosis in a patient treated with risperidone
by Steven Fong, Alex Bazeos, Julia Thomas and Tahseen A. Chowdhury
Diabetic ketoacidosis (DKA) is a life-threatening complication of diabetes. The development of metabolic syndrome is widely recognised with the use of atypical antipsychotic agents, and not infrequently DKA has been described with some of these drugs. We describe a complex patient with HIV who presented with severe DKA and prolonged hyperchloraemic acidosis, which we postulate was associated with risperidone therapy. (Specialties Endocrinology: 26th June 2008) More...

Parathyroid incidentalomas: case report and literature review
by A. Hotouras and P. Sinha
We report the case of a 60-year-old woman with a multinodular goitre who underwent total thyroidectomy and was found intraoperatively to have a parathyroid ‘incidentaloma’. The surgical approach to the management of patients with incidental parathyroid disease is discussed and a review of the literature is presented. (ENT/Head Neck Surgery, General Surgery, Endocrinology; 14th May 2007) More...

Hypothyroidism presenting as recurrence of previously surgically decompressed carpal tunnel syndrome
by V. Reid, A. S. M. Jawad and J. D. Perry
We report the case history of a 45-year-old woman who presented with symptoms of bilateral carpal tunnel syndrome 8 years after a successful surgical decompression of both tunnels. (Endocrinology, General surgery; April 2005) More...

Thomas Addison and his disease by A.B Grossman
Thomas Addison’s description of the disease named after him first appears in a book entitled ‘On the constitutional and local effects of disease of the supra-renal capsules’ published by Samuel Highley of 32 Fleet Street London in 1855. (Endocrinology; Landmark Case Reports; May 2004) More...

Harvey Cushing and Cushing's syndrome by Ashley B. Grossman
Harvey Cushing's first description of the eponymous disease attributed to him is reproduced here together with a modern commentary.(Endocrinology; Landmark Case Report; September 2004) More...

Painful Leg and Loss of Vision in a Diabetic
A case of recurrent bacteraemia due to Staphylococcus aureus with associated pyomyositis and endophthalmitis in an insulin-dependent diabetic with chronic liver disease secondary to alcohol abuse. (July 2002) More...